JITMM Pre-Meeting Course is now open!
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JITMM Pre-meeting Course will offer the updated knowledge on clinical and laboratory of 3 tropical diseases i.e. 1) malaria drug resistant, 2) amoeba/Free-living amoeba infections and 3) toxoplasmosis. The advance in biology, clinical relevance, diagnosis and treatment on those diseases as well as hands-on lab and data analysis sessions will be covered. Clinicians and experienced researchers will also be available for discussions.
Participants will attend lectures, on 3 diseases, which will be delivered by hand-on experienced clinicians and select to join only one laboratory demonstration/workshop.
1) Antimalarial drug resistance
Artemisinin resistant falciparum malaria originated on the Cambodian-Thai border and has since then emerged in 5 countries of the Greater Mekong Subregion. In addition, resistance of the parasite to the partner drugs in the artemisinin combination therapies is a rapidly increasing problem, causing alarmingly high treatment failure rates in several regions and leaving only very limited treatment options. This is obviously an enormous threat to malaria control. Knowledge on the biological and genetic determinants of artemisinin resistance has increased significantly recently, and has provided useful tools for surveillance.
This course will provide an update on a broad range of aspects related to artemisinin and multi-drug resistant falciparum malaria. This includes molecular genetics, cell biology, laboratory aspects, clinical aspects including treatment options, epidemiology, as well as potential strategies to counter this emergency.
Lectures with ample opportunity for discussion will be delivered by Prof. Dr. Arjen Dondorp, and a lab demonstration and workshop will illustrating molecular genetic research into the problem of antimalarial drug resistance by Assoc. Prof. Dr. Malika Imwong and her team.
2) Amoeba/Free-Living Amoeba infection
Among amoebae infections, only Entamoeba histolytica causes gastro-intestinal manifestations. The number of case is decreasing, however, it is still presence in Southeast Asian region. Amoebic liver abscess is the most consequence of extra-intestinal infection. Cases will be presented for interactive discussion in term of clinical features, diagnosis, treatment, prevention and control.
Free-living amoeba, Naegleria fowleri, infection is rare but fatal. It is the causative agent of primary amebic meningoencephalitis or PAM. To manage PAM cases is a challenge due to the serious and acute natural history. Thai cases will be shown for learning and sharing experiences.
To share and learn from hand-on clinicians on amoebae and free-lining amoeba cases concerning clinical manifestations, diagnosis, treatment and prevention & control measures.
Group of clinicians, led by Assoc. Prof. Dr. Yupaporn Wattanagoon, Dr. Chatporn Kittitrakul and Dr. Kittiyod Poovorawan, will provide cases presentation for discussion. Laboratory molecular diagnostic procedures for species differentiation among amoebae will be demonstrated by Assoc. Prof. Dr. Porntip Petmitr and her team.
A LAMP assay for detecting N. fowleri, developed by Dr. Aongart Mahittikorn, is a simple, sensitive and highly specific technique. Participants will have a chance to observe, practice and discuss on adapting and adopting the LAMP for resource-poor settings or developing country laboratories.
Toxoplasmic encephalitis (TE) is the most common neurological opportunistic infections among HIV/AIDS causing sever sequale results in high mortality and morbidity. TE is the sixth-most-frequent condition associated with death in AIDS in Thailand, despite free access to HAART (highly active antiretroviral treatment). Diagnosis of TE case is a crucial for live-saving but it is not straight forward. In different clinical centers, specific treatment is usually initiated according to a presumptive diagnosis recommended by CDC, which is based on clinical and radiological findings.
To demonstrate Thai TE cases and provides discussion on clinical features, conventional and other laboratory options diagnostic procedures.
Clinicians, Prof. Dr. Yaowalark Sukthana and Asst. Prof. Dr. Viravarn Luvira, will lecture and demonstrate Thai TE cases. A gold standard serological Sabin-Feldman Dye test, Real-time PCR and stage-specific RT- PCR as conventional and options for TE diagnosis will be provided by Dr. Aongart Mahittikorn and Miss Ruenrutai Udonsom.
When & Where
Date & time: Tuesday, 1st December 2015, at 9:00-16:30
(lecture in the morning and laboratory demonstration/workshop in the afternoon)
Venue: Rajanagarindra Building, Faculty of Tropical Medicine, Mahidol University
420/6 Rachavithi Road, Bangkok 10400, THAILAND
Phone/Fax: +66 2306 9125
Capacity: Up to 100 participants for lecture but not more than 35 participants for each laboratory demonstration/workshop
Price: US$ 150 for lecture and laboratory demonstration/workshop. Please be noted that the registration is on a first come, first served basis.